Pediatric Diabetic Ketoacidosis-January 27, 2015

As part of its public awareness lectures series, new hospital organized an educational lecture about Pediatric Diabetic Ketoacidosis on Tuesday, January 27, 2015 to raise health awareness in the society by Dr. Ahmed Salem - Consultant & Clinical Director of Pediatrics & Neonatal Department. he talked about Diabetic Ketoacidosis (Definition / Pathophysiology / Clinical manifestations / Treatment / Complications) first of all what is the Definition of Diabetic Ketoacidosis it is Blood glucose level > 200 mg/dl, Blood pH < 7.3, HCO3 < 20 mEq/L, Anion Gap > 12 & Elevated serum or urine ketones.

Pathophysiology of carbohydrate metabolism Glucose and lipid metabolism are regulated by insulin, and its counter regulatory hormones:

• Glucagon
• Catecholamines
• Cortisol
• Growth hormone

The Clinical manifestations (Classic triad: polydipsia, polyuria, polyphagia, Weight loss, Nausea, vomiting and abdominal pain, Changes in breathing pattern & Precipitating event: infection, psychosocial stress). Treatment (Manage with oral hydration + S.C. Insulin, Use routine S.C. Insulin regimens & the Laboratory assessment is not needed). the Complications (Dehydration, Hypotension / Shock, Hypokalemia, hyperkalemia, Hypoglycemia, Aspiration pneumonia, Sepsis, Acute tubular necrosis, Cerebral edema)